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Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression

Cardiovascular diseases are risk factors for depression in humans. We recently proposed that σ(1) receptor (σ(1)R) stimulation rescued cardiac hypertrophy and heart failure induced by transverse aortic constriction (TAC) in mice. Importantly, σ(1)R stimulation reportedly ameliorates depression-like...

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Detalles Bibliográficos
Autores principales:	Shinoda, Yasuharu, Tagashira, Hideaki, Bhuiyan, Md. Shenuarin, Hasegawa, Hideyuki, Kanai, Hiroshi, Zhang, Chen, Han, Feng, Fukunaga, Kohji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065174/ https://www.ncbi.nlm.nih.gov/pubmed/27741227 http://dx.doi.org/10.1371/journal.pone.0163992

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