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Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan-Neuronal Activation in the Female Mouse

Gender difference in Parkinson’s disease (PD) suggests that female sex steroids may promote dopaminergic neuron survival and protect them from degeneration. The glial cell line-derived neurotrophic factor (GDNF) is believed to be dopaminotrophic; thus it is considered as a potential therapeutic targ...

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Detalles Bibliográficos
Autores principales: Enterría-Morales, Daniel, López-López, Ivette, López-Barneo, José, d’Anglemont de Tassigny, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065215/
https://www.ncbi.nlm.nih.gov/pubmed/27741271
http://dx.doi.org/10.1371/journal.pone.0164391