TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1

DNA repair pathways enable cancer cells to survive DNA damage induced after genotoxic therapies. Tyrosine kinase receptors (TKRs) have been reported as regulators of the DNA repair machinery. TIE2 is a TKR overexpressed in human gliomas at levels that correlate with the degree of increasing malignan...

Descripción completa

Detalles Bibliográficos
Autores principales: Hossain, Mohammad B., Shifat, Rehnuma, Johnson, David G., Bedford, Mark T., Gabrusiewicz, Konrad R., Cortes-Santiago, Nahir, Luo, Xuemei, Lu, Zhimin, Ezhilarasan, Ravesanker, Sulman, Erik P., Jiang, Hong, Li, Shawn S. C., Lang, Frederick F., Tyler, Jessica, Hung, Mien-Chie, Fueyo, Juan, Gomez-Manzano, Candelaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065225/
https://www.ncbi.nlm.nih.gov/pubmed/27757426
http://dx.doi.org/10.1126/sciadv.1501290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065225/
https://www.ncbi.nlm.nih.gov/pubmed/27757426
http://dx.doi.org/10.1126/sciadv.1501290

Ejemplares similares