MyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity

Therapeutic DNA-based vaccines aim to prime an adaptive host immune response against tumor-associated antigens, eliminating cancer cells primarily through CD8(+) cytotoxic T cell-mediated destruction. To be optimally effective, immunological adjuvants are required for the activation of tumor-specifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Collinson-Pautz, Matthew R., Slawin, Kevin M., Levitt, Jonathan M., Spencer, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065236/
https://www.ncbi.nlm.nih.gov/pubmed/27741278
http://dx.doi.org/10.1371/journal.pone.0164547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065236/
https://www.ncbi.nlm.nih.gov/pubmed/27741278
http://dx.doi.org/10.1371/journal.pone.0164547

Ejemplares similares