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RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

Polycomb group (PcG) proteins function as chromatin-based transcriptional repressors that are essential for normal gene regulation during development. However, how these systems function to achieve transcriptional regulation remains very poorly understood. Here, we discover that the histone H2AK119...

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Detalles Bibliográficos
Autores principales: Rose, Nathan R, King, Hamish W, Blackledge, Neil P, Fursova, Nadezda A, Ember, Katherine JI, Fischer, Roman, Kessler, Benedikt M, Klose, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065315/
https://www.ncbi.nlm.nih.gov/pubmed/27705745
http://dx.doi.org/10.7554/eLife.18591