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Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope

The nuclear pore complex (NPC) mediates nucleocytoplasmic transport through the nuclear envelope. How the NPC assembles into this double membrane boundary has remained enigmatic. Here, we captured temporally staged assembly intermediates by correlating live cell imaging with high-resolution electron...

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Detalles Bibliográficos
Autores principales: Otsuka, Shotaro, Bui, Khanh Huy, Schorb, Martin, Hossain, M Julius, Politi, Antonio Z, Koch, Birgit, Eltsov, Mikhail, Beck, Martin, Ellenberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065316/
https://www.ncbi.nlm.nih.gov/pubmed/27630123
http://dx.doi.org/10.7554/eLife.19071