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Physical Proximity of Sister Chromatids Promotes Top2-Dependent Intertwining

Sister chromatid intertwines (SCIs), or catenanes, are topological links between replicated chromatids that interfere with chromosome segregation. The formation of SCIs is thought to be a consequence of fork swiveling during DNA replication, and their removal is thought to occur because of the intri...

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Detalles Bibliográficos
Autores principales: Sen, Nicholas, Leonard, Joanne, Torres, Raul, Garcia-Luis, Jonay, Palou-Marin, Gloria, Aragón, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065527/
https://www.ncbi.nlm.nih.gov/pubmed/27716481
http://dx.doi.org/10.1016/j.molcel.2016.09.007