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Physical Proximity of Sister Chromatids Promotes Top2-Dependent Intertwining
Sister chromatid intertwines (SCIs), or catenanes, are topological links between replicated chromatids that interfere with chromosome segregation. The formation of SCIs is thought to be a consequence of fork swiveling during DNA replication, and their removal is thought to occur because of the intri...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065527/ https://www.ncbi.nlm.nih.gov/pubmed/27716481 http://dx.doi.org/10.1016/j.molcel.2016.09.007 |