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Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled
Extracellular signals are often transduced by dynamic signaling complexes (“signalosomes”) assembled by oligomerizing hub proteins following their recruitment to signal-activated transmembrane receptors. A paradigm is the Wnt signalosome, which is assembled by Dishevelled via reversible head-to-tail...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065529/ https://www.ncbi.nlm.nih.gov/pubmed/27692984 http://dx.doi.org/10.1016/j.molcel.2016.08.026 |