A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis

Several shortcomings of current Parkinson’s disease (PD) models limit progress in identification of environmental contributions to disease pathogenesis. The conditionally immortalized cell line LUHMES promises to make human dopaminergic neuronal cultures more easily available, but these cells are di...

Descripción completa

Detalles Bibliográficos
Autores principales: Smirnova, L., Harris, G., Delp, J., Valadares, M., Pamies, D., Hogberg, H. T., Waldmann, T., Leist, M., Hartung, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
In Vitro Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065586/
https://www.ncbi.nlm.nih.gov/pubmed/26647301
http://dx.doi.org/10.1007/s00204-015-1637-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065586/
https://www.ncbi.nlm.nih.gov/pubmed/26647301
http://dx.doi.org/10.1007/s00204-015-1637-z

Ejemplares similares