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Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice

Oxidative stress plays an important role in cerebral ischemia–reperfusion injury. Dimethyl fumarate (DMF) and its primary metabolite monomethyl fumarate (MMF) are antioxidant agents that can activate the nuclear factor erythroid-2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway and induce th...

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Detalles Bibliográficos
Autores principales: Yao, Yang, Miao, Weimin, Liu, Zhijia, Han, Wei, Shi, Kaibin, Shen, Yi, Li, Handong, Liu, Qiang, Fu, Ying, Huang, DeRen, Shi, Fu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065588/
https://www.ncbi.nlm.nih.gov/pubmed/27614618
http://dx.doi.org/10.1007/s12975-016-0496-0