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High-throughput imaging-based nephrotoxicity prediction for xenobiotics with diverse chemical structures

The kidney is a major target for xenobiotics, which include drugs, industrial chemicals, environmental toxicants and other compounds. Accurate methods for screening large numbers of potentially nephrotoxic xenobiotics with diverse chemical structures are currently not available. Here, we describe an...

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Detalles Bibliográficos
Autores principales: Su, Ran, Xiong, Sijing, Zink, Daniele, Loo, Lit-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065616/
https://www.ncbi.nlm.nih.gov/pubmed/26612367
http://dx.doi.org/10.1007/s00204-015-1638-y