Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential

Acetaminophen (APAP) hepatotoxicity is characterized by an extensive oxidative stress. However, its source, pathophysiological role and possible therapeutic potential if targeted, have been controversially described. Earlier studies argued for cytochrome P450-generated reactive oxygen species (ROS)...

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Detalles Bibliográficos
Autores principales: Du, Kuo, Ramachandran, Anup, Jaeschke, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065645/
https://www.ncbi.nlm.nih.gov/pubmed/27744120
http://dx.doi.org/10.1016/j.redox.2016.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065645/
https://www.ncbi.nlm.nih.gov/pubmed/27744120
http://dx.doi.org/10.1016/j.redox.2016.10.001

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