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Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential
Acetaminophen (APAP) hepatotoxicity is characterized by an extensive oxidative stress. However, its source, pathophysiological role and possible therapeutic potential if targeted, have been controversially described. Earlier studies argued for cytochrome P450-generated reactive oxygen species (ROS)...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065645/ https://www.ncbi.nlm.nih.gov/pubmed/27744120 http://dx.doi.org/10.1016/j.redox.2016.10.001 |