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The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration

Retinitis pigmentosa (RP) is one of the most common retinal degenerative conditions affecting people worldwide, and is currently incurable. It is characterized by the progressive loss of photoreceptors, in which the death of rod cells leads to the secondary death of cone cells; the cause of eventual...

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Detalles Bibliográficos
Autores principales: Byrne, Ashleigh M., Ruiz-Lopez, Ana M., Roche, Sarah L., Moloney, Jennifer N., Wyse -Jackson, Alice C., Cotter, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065647/
https://www.ncbi.nlm.nih.gov/pubmed/27744118
http://dx.doi.org/10.1016/j.redox.2016.10.002