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The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration
Retinitis pigmentosa (RP) is one of the most common retinal degenerative conditions affecting people worldwide, and is currently incurable. It is characterized by the progressive loss of photoreceptors, in which the death of rod cells leads to the secondary death of cone cells; the cause of eventual...
Autores principales: | Byrne, Ashleigh M., Ruiz-Lopez, Ana M., Roche, Sarah L., Moloney, Jennifer N., Wyse -Jackson, Alice C., Cotter, Thomas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065647/ https://www.ncbi.nlm.nih.gov/pubmed/27744118 http://dx.doi.org/10.1016/j.redox.2016.10.002 |
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