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Cellular proteostasis: degradation of misfolded proteins by lysosomes

Proteostasis refers to the regulation of the cellular concentration, folding, interactions and localization of each of the proteins that comprise the proteome. One essential element of proteostasis is the disposal of misfolded proteins by the cellular pathways of protein degradation. Lysosomes are a...

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Detalles Bibliográficos
Autores principales: Jackson, Matthew P., Hewitt, Eric W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Limited 2016
Materias:
46
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065703/
https://www.ncbi.nlm.nih.gov/pubmed/27744333
http://dx.doi.org/10.1042/EBC20160005