Huperzine A Provides Robust and Sustained Protection against Induced Seizures in Scn1a Mutant Mice

De novo loss-of-function mutations in the voltage-gated sodium channel (VGSC) SCN1A (encoding Na(v)1.1) are the main cause of Dravet syndrome (DS), a catastrophic early-life encephalopathy associated with prolonged and recurrent early-life febrile seizures (FSs), refractory afebrile epilepsy, cognit...

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Detalles Bibliográficos
Autores principales: Wong, Jennifer C., Dutton, Stacey B. B., Collins, Stephen D., Schachter, Steven, Escayg, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065986/
https://www.ncbi.nlm.nih.gov/pubmed/27799911
http://dx.doi.org/10.3389/fphar.2016.00357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065986/
https://www.ncbi.nlm.nih.gov/pubmed/27799911
http://dx.doi.org/10.3389/fphar.2016.00357

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