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Huperzine A Provides Robust and Sustained Protection against Induced Seizures in Scn1a Mutant Mice
De novo loss-of-function mutations in the voltage-gated sodium channel (VGSC) SCN1A (encoding Na(v)1.1) are the main cause of Dravet syndrome (DS), a catastrophic early-life encephalopathy associated with prolonged and recurrent early-life febrile seizures (FSs), refractory afebrile epilepsy, cognit...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065986/ https://www.ncbi.nlm.nih.gov/pubmed/27799911 http://dx.doi.org/10.3389/fphar.2016.00357 |