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Understanding Mechanisms of GLI-Mediated Transcription during Craniofacial Development and Disease Using the Ciliopathic Mutant, talpid(2)

The primary cilium is a ubiquitous, microtubule-based organelle that cells utilize to transduce molecular signals. Ciliopathies are a group of diseases that are caused by a disruption in the structure or function of the primary cilium. Over 30% of all ciliopathies are primarily defined by their cran...

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Detalles Bibliográficos
Autores principales: Chang, Ya-Ting, Chaturvedi, Praneet, Schock, Elizabeth N., Brugmann, Samantha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065992/
https://www.ncbi.nlm.nih.gov/pubmed/27799912
http://dx.doi.org/10.3389/fphys.2016.00468