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Establishment and functions of DNA methylation in the germline

Epigenetic modifications established during gametogenesis regulate transcription and other nuclear processes in gametes, but also have influences in the zygote, embryo and postnatal life. This is best understood for DNA methylation which, established at discrete regions of the oocyte and sperm genom...

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Detalles Bibliográficos
Autores principales: Stewart, Kathleen R, Veselovska, Lenka, Kelsey, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066131/
https://www.ncbi.nlm.nih.gov/pubmed/27659720
http://dx.doi.org/10.2217/epi-2016-0056