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Z-DNA-forming sites identified by ChIP-Seq are associated with actively transcribed regions in the human genome

Z-DNA, a left-handed double helical DNA is structurally different from the most abundant B-DNA. Z-DNA has been known to play a significant role in transcription and genome stability but the biological meaning and positions of Z-DNA-forming sites (ZFSs) in the human genome has not been fully explored...

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Detalles Bibliográficos
Autores principales: Shin, So-I., Ham, Seokjin, Park, Jihwan, Seo, Seong Hye, Lim, Chae Hyun, Jeon, Hyeongrin, Huh, Jounghyun, Roh, Tae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066173/
https://www.ncbi.nlm.nih.gov/pubmed/27374614
http://dx.doi.org/10.1093/dnares/dsw031