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Vectorization of biomacromolecules into cells using extracellular vesicles with enhanced internalization induced by macropinocytosis

Extracellular vesicles (EVs, exosomes) are approximately 30- to 200-nm-long vesicles that have received increased attention due to their role in cell-to-cell communication. Although EVs are highly anticipated to be a next-generation intracellular delivery tool because of their pharmaceutical advanta...

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Detalles Bibliográficos
Autores principales: Nakase, Ikuhiko, Noguchi, Kosuke, Fujii, Ikuo, Futaki, Shiroh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066177/
https://www.ncbi.nlm.nih.gov/pubmed/27748399
http://dx.doi.org/10.1038/srep34937