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Condensin I-mediated mitotic chromosome assembly requires association with chromokinesin KIF4A

The chromokinesin KIF4A has been implicated in shaping mitotic chromosomes, but its functional relationship to condensin complexes remains controversial. Here, we found that, in mitosis, KIF4A associates with condensin I but not with condensin II. Mutational analyses indicated that the enrichment of...

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Detalles Bibliográficos
Autores principales: Takahashi, Motoko, Wakai, Toshifumi, Hirota, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066236/
https://www.ncbi.nlm.nih.gov/pubmed/27633014
http://dx.doi.org/10.1101/gad.282855.116