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Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells

Multiple transcriptional and epigenetic changes drive differentiation of embryonic stem cells (ESCs). This study unveils an additional level of gene expression regulation involving noncanonical, cap-independent translation of a select group of mRNAs. This is driven by death-associated protein 5 (DAP...

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Detalles Bibliográficos
Autores principales: Yoffe, Yael, David, Maya, Kalaora, Rinat, Povodovski, Lital, Friedlander, Gilgi, Feldmesser, Ester, Ainbinder, Elena, Saada, Ann, Bialik, Shani, Kimchi, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066241/
https://www.ncbi.nlm.nih.gov/pubmed/27664238
http://dx.doi.org/10.1101/gad.285239.116