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Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp

In mammals, body temperature fluctuates diurnally around a mean value of 36°C–37°C. Despite the small differences between minimal and maximal values, body temperature rhythms can drive robust cycles in gene expression in cultured cells and, likely, animals. Here we studied the mechanisms responsible...

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Detalles Bibliográficos
Autores principales: Gotic, Ivana, Omidi, Saeed, Fleury-Olela, Fabienne, Molina, Nacho, Naef, Felix, Schibler, Ueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066242/
https://www.ncbi.nlm.nih.gov/pubmed/27633015
http://dx.doi.org/10.1101/gad.287094.116