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The complete salmonid IGF-IR gene repertoire and its transcriptional response to disease

The insulin-like growth factor (IGF) receptor (IGF-IR) is necessary for IGF signalling and has essential roles in cellular growth. In teleost fish, two distinct IGF-IR duplicates are conserved called IGF-IRa and IGF-IRb. However, while a salmonid-specific whole genome duplication (ssWGD) is known to...

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Detalles Bibliográficos
Autores principales: Alzaid, Abdullah, Martin, Samuel A. M., Macqueen, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066257/
https://www.ncbi.nlm.nih.gov/pubmed/27748369
http://dx.doi.org/10.1038/srep34806