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Involvement of Brain-Enriched Guanylate Kinase-Associated Protein (BEGAIN) in Chronic Pain after Peripheral Nerve Injury

Maintenance of neuropathic pain caused by peripheral nerve injury crucially depends on the phosphorylation of GluN2B, a subunit of the N-methyl-d-aspartate (NMDA) receptor, at Tyr1472 (Y1472) and subsequent formation of a postsynaptic density (PSD) complex of superficial spinal dorsal horn neurons....

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Detalles Bibliográficos
Autores principales: Katano, Tayo, Fukuda, Masafumi, Furue, Hidemasa, Yamazaki, Maya, Abe, Manabu, Watanabe, Masahiko, Nishida, Kazuhiko, Yao, Ikuko, Yamada, Akihiro, Hata, Yutaka, Okumura, Nobuaki, Nakazawa, Takanobu, Yamamoto, Tadashi, Sakimura, Kenji, Takao, Toshifumi, Ito, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066261/
https://www.ncbi.nlm.nih.gov/pubmed/27785460
http://dx.doi.org/10.1523/ENEURO.0110-16.2016