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Activation of a Habenulo–Raphe Circuit Is Critical for the Behavioral and Neurochemical Consequences of Uncontrollable Stress in the Male Rat

Exposure to uncontrollable stress [inescapable tailshock (IS)] produces behavioral changes that do not occur if the stressor is controllable [escapable tailshock (ES)] an outcome that is mediated by greater IS-induced dorsal raphe nucleus (DRN) serotonin [5-hydroxytryptamine (5-HT)] activation. It h...

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Detalles Bibliográficos
Autores principales: Dolzani, Samuel D., Baratta, Michael V., Amat, Jose, Agster, Kara L., Saddoris, Michael P., Watkins, Linda R., Maier, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066263/
https://www.ncbi.nlm.nih.gov/pubmed/27785462
http://dx.doi.org/10.1523/ENEURO.0229-16.2016