A simple and efficient method to visualize and quantify the efficiency of chromosomal mutations from genome editing

Genome editing with designer nucleases such as TALEN and CRISPR/Cas enzymes has broad applications. Delivery of these designer nucleases into organisms induces various genetic mutations including deletions, insertions and nucleotide substitutions. Characterizing those mutations is critical for evalu...

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Detalles Bibliográficos
Autores principales: Fu, Liezhen, Wen, Luan, Luu, Nga, Shi, Yun-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066342/
https://www.ncbi.nlm.nih.gov/pubmed/27748423
http://dx.doi.org/10.1038/srep35488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066342/
https://www.ncbi.nlm.nih.gov/pubmed/27748423
http://dx.doi.org/10.1038/srep35488

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