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A simple and efficient method to visualize and quantify the efficiency of chromosomal mutations from genome editing
Genome editing with designer nucleases such as TALEN and CRISPR/Cas enzymes has broad applications. Delivery of these designer nucleases into organisms induces various genetic mutations including deletions, insertions and nucleotide substitutions. Characterizing those mutations is critical for evalu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066342/ https://www.ncbi.nlm.nih.gov/pubmed/27748423 http://dx.doi.org/10.1038/srep35488 |