Cargando…

DUSP11 activity on triphosphorylated transcripts promotes Argonaute association with noncanonical viral microRNAs and regulates steady-state levels of cellular noncoding RNAs

RNA silencing is a conserved eukaryotic gene expression regulatory mechanism mediated by small RNAs. In Caenorhabditis elegans, the accumulation of a distinct class of siRNAs synthesized by an RNA-dependent RNA polymerase (RdRP) requires the PIR-1 phosphatase. However, the function of PIR-1 in RNAi...

Descripción completa

Detalles Bibliográficos
Autores principales: Burke, James M., Kincaid, Rodney P., Nottingham, Ryan M., Lambowitz, Alan M., Sullivan, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066614/
https://www.ncbi.nlm.nih.gov/pubmed/27798849
http://dx.doi.org/10.1101/gad.282616.116