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Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture
Mediator is a large coregulator complex conserved from yeast to humans and involved in many human diseases, including cancers. Together with general transcription factors, it stimulates preinitiation complex (PIC) formation and activates RNA polymerase II (Pol II) transcription. In this study, we an...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066617/ https://www.ncbi.nlm.nih.gov/pubmed/27688401 http://dx.doi.org/10.1101/gad.285775.116 |