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Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture

Mediator is a large coregulator complex conserved from yeast to humans and involved in many human diseases, including cancers. Together with general transcription factors, it stimulates preinitiation complex (PIC) formation and activates RNA polymerase II (Pol II) transcription. In this study, we an...

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Detalles Bibliográficos
Autores principales:	Eychenne, Thomas, Novikova, Elizaveta, Barrault, Marie-Bénédicte, Alibert, Olivier, Boschiero, Claire, Peixeiro, Nuno, Cornu, David, Redeker, Virginie, Kuras, Laurent, Nicolas, Pierre, Werner, Michel, Soutourina, Julie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066617/ https://www.ncbi.nlm.nih.gov/pubmed/27688401 http://dx.doi.org/10.1101/gad.285775.116

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