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Codon optimality controls differential mRNA translation during amino acid starvation

It is common wisdom that codon usage bias has evolved in the selection for efficient translation, in which highly expressed genes are encoded predominantly by optimal codons. However, a growing body of evidence suggests regulatory roles for non-optimal codons in translation dynamics. Here we report...

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Detalles Bibliográficos
Autores principales: Saikia, Mridusmita, Wang, Xiaoyun, Mao, Yuanhui, Wan, Ji, Pan, Tao, Qian, Shu-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066624/
https://www.ncbi.nlm.nih.gov/pubmed/27613579
http://dx.doi.org/10.1261/rna.058180.116