tRNA base methylation identification and quantification via high-throughput sequencing

Eukaryotic transfer RNAs contain on average 14 modifications. Investigations of their biological functions require the determination of the modification sites and the dynamic variations of the modification fraction. Base methylation represents a major class of tRNA modification. Although many approa...

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Detalles Bibliográficos
Autores principales: Clark, Wesley C., Evans, Molly E., Dominissini, Dan, Zheng, Guanqun, Pan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066629/
https://www.ncbi.nlm.nih.gov/pubmed/27613580
http://dx.doi.org/10.1261/rna.056531.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066629/
https://www.ncbi.nlm.nih.gov/pubmed/27613580
http://dx.doi.org/10.1261/rna.056531.116

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