Apparent subadditivity of the efficacy of initial combination treatments for type 2 diabetes is largely explained by the impact of baseline HbA1c on efficacy

AIM: To explain the subadditive efficacy typically observed with initial combination treatments for type 2 diabetes. METHODS: Individual subject data from 1186 patients with type 2 diabetes [mean glycated haemoglobin (HbA1c) = 8.8%] treated with metformin, canagliflozin or canagliflozin + metformin...

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Detalles Bibliográficos
Autores principales: Polidori, D., Capuano, G., Qiu, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066661/
https://www.ncbi.nlm.nih.gov/pubmed/26661906
http://dx.doi.org/10.1111/dom.12615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066661/
https://www.ncbi.nlm.nih.gov/pubmed/26661906
http://dx.doi.org/10.1111/dom.12615

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