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The evolutionary adaptation of the C282Y mutation to culture and climate during the European Neolithic

OBJECTIVES: The C282Y allele is the major cause of hemochromatosis as a result of excessive iron absorption. The mutation arose in continental Europe no earlier than 6,000 years ago, coinciding with the arrival of the Neolithic agricultural revolution. Here we hypothesize that this new Neolithic die...

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Detalles Bibliográficos
Autores principales: Heath, Kathleen M., Axton, Jacob H., McCullough, John M., Harris, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066702/
https://www.ncbi.nlm.nih.gov/pubmed/26799452
http://dx.doi.org/10.1002/ajpa.22937