Phase 1 Study of Safety, Tolerability, and Pharmacokinetics of PTC299, an Inhibitor of Stress‐Regulated Protein Translation

PTC299 is a novel small molecule that specifically blocks the production of protein from selected mRNAs that under certain conditions use noncanonical ribosomal translational pathways. Hypoxia, oncogenic transformation, and viral infections limit normal translation and turn on these noncanonical tra...

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Detalles Bibliográficos
Autores principales: Weetall, Marla, Davis, Thomas, Elfring, Gary, Northcutt, Valerie, Cao, Liangxian, Moon, Young‐Choon, Riebling, Peter, Dali, Mandar, Hirawat, Samit, Babiak, John, Colacino, Joseph, Almstead, Neil, Spiegel, Robert, Peltz, Stuart W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066743/
https://www.ncbi.nlm.nih.gov/pubmed/27310330
http://dx.doi.org/10.1002/cpdd.240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066743/
https://www.ncbi.nlm.nih.gov/pubmed/27310330
http://dx.doi.org/10.1002/cpdd.240

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