Cargando…

Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress

Engrailed homeoproteins are expressed in adult dopaminergic neurons of the substantia nigra. In Engrailed1 heterozygous mice, these neurons start dying at 6 weeks, are more sensitive to oxidative stress, and progressively develop traits similar to those observed following an acute and strong oxidati...

Descripción completa

Detalles Bibliográficos
Autores principales: Rekaik, Hocine, Blaudin de Thé, François-Xavier, Fuchs, Julia, Massiani-Beaudoin, Olivia, Prochiantz, Alain, Joshi, Rajiv L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066840/
https://www.ncbi.nlm.nih.gov/pubmed/26411690
http://dx.doi.org/10.1016/j.celrep.2015.08.076