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Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress
Engrailed homeoproteins are expressed in adult dopaminergic neurons of the substantia nigra. In Engrailed1 heterozygous mice, these neurons start dying at 6 weeks, are more sensitive to oxidative stress, and progressively develop traits similar to those observed following an acute and strong oxidati...
Autores principales: | Rekaik, Hocine, Blaudin de Thé, François-Xavier, Fuchs, Julia, Massiani-Beaudoin, Olivia, Prochiantz, Alain, Joshi, Rajiv L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066840/ https://www.ncbi.nlm.nih.gov/pubmed/26411690 http://dx.doi.org/10.1016/j.celrep.2015.08.076 |
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