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Insights into the pathogenesis of Langerhans cell histiocytosis: the development of targeted therapies

More than a century after its first description, Langerhans cell histiocytosis (LCH) still remains an intriguing disease. Considerable progress in understanding its biology has been achieved recently. Description of the V600E BRAF mutation in samples of LCH tissue in 2010 was followed by description...

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Detalles Bibliográficos
Autores principales: Hutter, Caroline, Minkov, Milen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066850/
https://www.ncbi.nlm.nih.gov/pubmed/27785447
http://dx.doi.org/10.2147/ITT.S91058