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Intracellular redox-responsive nanocarrier for plasmid delivery: in vitro characterization and in vivo studies in mice

Although some modifications of polyethyleneimine (PEI) properties have been explored to balance the transfection efficiency and cytotoxicity, its successful plasmid delivery in vitro and in vivo to realize its true therapeutic potentials remains a major challenge, mainly due to intracellular traffic...

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Detalles Bibliográficos
Autores principales: Zhang, Lifen, Zhang, Yushun, Chen, Zhenzhen, He, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066853/
https://www.ncbi.nlm.nih.gov/pubmed/27785025
http://dx.doi.org/10.2147/IJN.S94995