Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

Environmental exposure to silica nanoparticles (SiNPs) is inevitable due to their widespread application in industrial, commercial, and biomedical fields. In recent years, most investigators focus on the evaluation of cardiovascular effects of SiNPs in vivo and in vitro. Endothelial injury and dysfu...

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Detalles Bibliográficos
Autores principales: Guo, Caixia, Yang, Man, Jing, Li, Wang, Ji, Yu, Yang, Li, Yang, Duan, Junchao, Zhou, Xianqing, Li, Yanbo, Sun, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066858/
https://www.ncbi.nlm.nih.gov/pubmed/27785026
http://dx.doi.org/10.2147/IJN.S112030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066858/
https://www.ncbi.nlm.nih.gov/pubmed/27785026
http://dx.doi.org/10.2147/IJN.S112030

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