GE11 peptide modified and reduction-responsive hyaluronic acid-based nanoparticles induced higher efficacy of doxorubicin for breast carcinoma therapy

Novel breast carcinoma dual-targeted redox-responsive nanoparticles (NPs) based on cholesteryl-hyaluronic acid conjugates were designed for intracellular delivery of the antitumor drug doxorubicin (DOX). A series of reduction-responsive hyaluronic acid derivatives grafted with hydrophobic cholestery...

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Detalles Bibliográficos
Autores principales: Hu, Danrong, Mezghrani, Omar, Zhang, Lei, Chen, Yi, Ke, Xue, Ci, Tianyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066865/
https://www.ncbi.nlm.nih.gov/pubmed/27785019
http://dx.doi.org/10.2147/IJN.S113469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066865/
https://www.ncbi.nlm.nih.gov/pubmed/27785019
http://dx.doi.org/10.2147/IJN.S113469

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