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GE11 peptide modified and reduction-responsive hyaluronic acid-based nanoparticles induced higher efficacy of doxorubicin for breast carcinoma therapy
Novel breast carcinoma dual-targeted redox-responsive nanoparticles (NPs) based on cholesteryl-hyaluronic acid conjugates were designed for intracellular delivery of the antitumor drug doxorubicin (DOX). A series of reduction-responsive hyaluronic acid derivatives grafted with hydrophobic cholestery...
Autores principales: | Hu, Danrong, Mezghrani, Omar, Zhang, Lei, Chen, Yi, Ke, Xue, Ci, Tianyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066865/ https://www.ncbi.nlm.nih.gov/pubmed/27785019 http://dx.doi.org/10.2147/IJN.S113469 |
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