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Novel IgG-Degrading Enzymes of the IgdE Protease Family Link Substrate Specificity to Host Tropism of Streptococcus Species

Recently we have discovered an IgG degrading enzyme of the endemic pig pathogen S. suis designated IgdE that is highly specific for porcine IgG. This protease is the founding member of a novel cysteine protease family assigned C113 in the MEROPS peptidase database. Bioinformatical analyses revealed...

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Detalles Bibliográficos
Autores principales: Spoerry, Christian, Hessle, Pontus, Lewis, Melanie J., Paton, Lois, Woof, Jenny M., von Pawel-Rammingen, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066943/
https://www.ncbi.nlm.nih.gov/pubmed/27749921
http://dx.doi.org/10.1371/journal.pone.0164809