PlexinD1 Is a Novel Transcriptional Target and Effector of Notch Signaling in Cancer Cells

The secreted semaphorin Sema3E controls cell migration and invasiveness in cancer cells. Sema3E-receptor, PlexinD1, is frequently upregulated in melanoma, breast, colon, ovarian and prostate cancers; however, the mechanisms underlying PlexinD1 upregulation and the downstream events elicited in tumor...

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Detalles Bibliográficos
Autores principales: Rehman, Michael, Gurrapu, Sreeharsha, Cagnoni, Gabriella, Capparuccia, Lorena, Tamagnone, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066946/
https://www.ncbi.nlm.nih.gov/pubmed/27749937
http://dx.doi.org/10.1371/journal.pone.0164660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066946/
https://www.ncbi.nlm.nih.gov/pubmed/27749937
http://dx.doi.org/10.1371/journal.pone.0164660

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