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PlexinD1 Is a Novel Transcriptional Target and Effector of Notch Signaling in Cancer Cells
The secreted semaphorin Sema3E controls cell migration and invasiveness in cancer cells. Sema3E-receptor, PlexinD1, is frequently upregulated in melanoma, breast, colon, ovarian and prostate cancers; however, the mechanisms underlying PlexinD1 upregulation and the downstream events elicited in tumor...
Autores principales: | Rehman, Michael, Gurrapu, Sreeharsha, Cagnoni, Gabriella, Capparuccia, Lorena, Tamagnone, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066946/ https://www.ncbi.nlm.nih.gov/pubmed/27749937 http://dx.doi.org/10.1371/journal.pone.0164660 |
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