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Likelihood-Based Inference of B Cell Clonal Families
The human immune system depends on a highly diverse collection of antibody-making B cells. B cell receptor sequence diversity is generated by a random recombination process called “rearrangement” forming progenitor B cells, then a Darwinian process of lineage diversification and selection called “af...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066976/ https://www.ncbi.nlm.nih.gov/pubmed/27749910 http://dx.doi.org/10.1371/journal.pcbi.1005086 |