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High-Throughput Analysis of Global DNA Methylation Using Methyl-Sensitive Digestion

DNA methylation is a major regulatory process of gene transcription, and aberrant DNA methylation is associated with various diseases including cancer. Many compounds have been reported to modify DNA methylation states. Despite increasing interest in the clinical application of drugs with epigenetic...

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Detalles Bibliográficos
Autores principales: Shiratori, Hiromi, Feinweber, Carmen, Knothe, Claudia, Lötsch, Jörn, Thomas, Dominique, Geisslinger, Gerd, Parnham, Michael J., Resch, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066982/
https://www.ncbi.nlm.nih.gov/pubmed/27749902
http://dx.doi.org/10.1371/journal.pone.0163184